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Comprehensive study of the coupling between substrate transport and ATP hydrolysis in P-glycoprotein and ABCG2
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Details of project
Identifier
124815
Type
K
Principal investigator
Goda, Katalin
Title in Hungarian
A szubsztrát transzport és ATP hidrolízis kapcsolatának átfogó vizsgálata a P-glikoprotein és ABCG2 transzporterekben
Title in English
Comprehensive study of the coupling between substrate transport and ATP hydrolysis in P-glycoprotein and ABCG2
Keywords in Hungarian
ABCB1, ABCG2, katalitikus ciklus, konformáció érzékeny antitest, konformáció változás, hely-specifikus mutagenezis
Keywords in English
ABCB1, ABCG2, catalytic cycle, conformation sensitive antibody, conformation changes, site-directed mutagenesis
Discipline
Biophysics (e.g. transport mechanisms, bioenergetics, fluorescence) (Council of Medical and Biological Sciences)
40 %
Ortelius classification:
Biophysics
General biochemistry and metabolism (Council of Medical and Biological Sciences)
30 %
Ortelius classification:
Enzimology
Molecular biology (Council of Medical and Biological Sciences)
30 %
Ortelius classification:
Molecular biology
Panel
Molecular and Structural Biology and Biochemistry
Department or equivalent
Department of Biophysics and Cell Biology (University of Debrecen)
Participants
Csősz, Éva
Gyöngy, Zsuzsanna
Kalló, Gergő
Ritter, Zsuzsanna
Szabó, Gábor
Szakács, Gergely
Tarapcsák, Szabolcs
Starting date
2017-09-01
Closing date
2023-03-31
Funding (in million HUF)
47.997
FTE (full time equivalent)
9.96
state
running project
Events of the project
2020-12-17 11:58:56
Résztvevők változása
2020-07-29 21:12:40
Résztvevők változása
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