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T cell activating Natural Killer cells (TaNK) as “off-the-shelf” biotherapeutic for HER2-positive solid tumors
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Details of project
Identifier
143771
Type
K
Principal investigator
Vereb, György
Title in Hungarian
T-sejteket aktiváló természetes ölősejtek (TaNK) HER2-pozitív szolid tumorok "off-the-shelf" biológiai terápiájára
Title in English
T cell activating Natural Killer cells (TaNK) as “off-the-shelf” biotherapeutic for HER2-positive solid tumors
Keywords in Hungarian
kiméra antigén receptor (CAR), NK sejt, bispecifikus T-sejt kapcsoló (BiTE), HER2, génszerkesztett immunsejt, célzott daganat immunterápia, élő gyógyszer
Keywords in English
chimeric antigen receptor (CAR), NK cell, bispecific T-cell engager (BiTE), HER2, gene-edited immune cell, targeted tumour immunotherapy, living drug
Discipline
Immunology (Council of Medical and Biological Sciences)
100 %
Panel
Immunity, Cancer and Microbiology
Department or equivalent
Department of Biophysics and Cell Biology (University of Debrecen)
Participants
Csaplár, Marianna
Gergely, Bence
Nagy, Lőrinc
Rebenku, István
Szöőr, Árpád
Ujlaky-Nagy, László
Starting date
2022-12-01
Closing date
2026-11-30
Funding (in million HUF)
48.000
FTE (full time equivalent)
8.00
state
running project
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