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Regulatory and catalytic mechanisms of oligopeptidases
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List of publications |
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Gouvea, I.E., Judice, W.A.S., Cezari, M.H.S., Juliano, M.A., Juhász, T., Szeltner, Z., Polgár, L., and Juliano,L.: Kosmotropic salt activation and substrate specificity of poliovirus 3C., Biochemistry 45, 12083-12089, 2006 | Polgár, L.: Catalytic mechanisms of serine and threonine peptidases., In: Handbook of Proteolytic Enzymes, 2 edn (Barrett,A.J., Rawlings,N.D. & Woessner,J.F. eds), chapter 439, p.1440-1448, Elsevier, London., 2004 | Polgár, L.: Catalytic mechanisms of cysteine peptidases, Handbook of Proteolytic Enzymes, 2 edn (Barrett,A.J., Rawlings,N.D. & Woessner,J.F. eds), chapter 332, p.1072-1079, Elsevier, London., 2004 | Wright, H., Szeltner, Z., Kiss, A., Polgár, L., and Fülöp, V.: Determination of the structure of serine-type protease acylaminoacyl peptidase, Acta Cryst. A60, s176, 2004 | Juhász, T., Szeltner, Z., Fülöp, V., and Polgár, L.: Unclosed -propellers display stable structures: Implications for substrate access to the active site of prolyl oligopeptidase, J. Mol. Biol. 346, 907-917., 2005 | Cheng, L., Lumb, M., Polgár, L., and Mudge A.W.: How can the mood stabilizer VPA limit both mania and depression., Molec. Cell. Neurosci. 29, 155-161., 2005 | Fuxreiter, M., Magyar, C., Juhász, T., Szeltner, Z., Polgár, L., and Simon, I.: Flexibility of prolyl oligopeptidase: molecular dynamics and molecular framework analysis of the potential substrate pathways, Proteins 60, 504-512, 2005 | Polgár, L.: The catalytic triad of serine peptidases., Cell. Mol. Life Sci. 62, 2161-2172, 2005 | Szeltner, Z., Alshafee, I., Juhász, Z., Parvari, R., and Polgár, L: The PREPL A protein, a new member of the prolyl oligopeptidase family, lacking catalytic activity., Cell. Mol. Life Sci. 62, 2376-2381, 2005 | Olah, J., Orosz, F., Puskas, L.G., Hackler, L., Jr., Horanyi, M., Polgar, L., Hollan, S., and Ovadi, J.: Triosephosphate isomerase deficiency: consequences of an inherited mutation at mRNA, protein and metabolic levels., Biochem. J. 392, 675-683, 2005 | Wright, H., Kiss, A.L., Szeltner, Z., Polgár, L., and Fülöp, V: Crystallization and preliminary crystallographic analysis of the porcine acylaminoacyl peptidase., Acta Cryst. F61, 942-944, 2005 | Juhász, T., Szeltner, Z., and Polgár, L.: Properties of the prolyl oligopeptidase homologue from Pyrococcus furiosus., FEBS Lett. 580, 3493-3497, 2006 | Kiss, A.L., Hornung, B., Rádi, K., Gengeliczki, Z., Sztáray, B., Juhász, T., Szeltner, Z., Harmat, V., and Polgár, L.: The acylaminoacyl peptidase from Aeropyrum pernix K1 thought to be an exopeptidase displays endopeptidase activity., J. Mol. Biol. 368, 509-520., 2007 | Kiss, A. L., Szeltner, Z., Fülöp, V., and Polgár, L.: His507 of acylaminoacyl peptidase stabilizes the active site conformation, not the catalytic intermediate, FEBS Lett. 571, 17-20., 2004 | Szeltner, Z., Rea, D., Renner, V., Juhász, T., Fülöp, V., and Polgár,: Concerted structural changes in the peptidase and the propeller domains of prolyl oligopeptidase are required for substrate binding., J. Mol. Biol. 340, 627-637., 2004 | Juhász, T., Szeltner, Z., and Polgár, L.: Truncated prolyl oligopeptidase from Pyrococcus furiosus., Proteins 69, 633-643., 2007 | Gorrão, S.S., Hemerly, J.P., Lima, A.R., Melo, R.L., Szeltner, Z., Polgár, L., Juliano, M.A., Juliano, L.: Fluorescence resonance energy transfer (FRET) peptides and cycloretro-inverso peptides derived from bradykinin as substrates and inhibitors of prolyl oligopeptidase., Peptides 28, 2146-2154, 2007 | Szeltner, Z., and Polgár, L.: Structure, function and biological relevance of prolyl oligopeptidase., Curr. Prot. Pept. Sci. 9, (közlésre elfogadva)., 2008 | Kiss, A.L, Palló, A., Náray-Szabó, G., Harmat, V. and Polgár, L: Structural and kinetic contribution of the oxyanion binding site to the catalytic activity of acylaminoacyl peptidase., J. Strut. Biol. (közlésre elfogadva)., 2008 |
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