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Proteolytic destruction of the thrombus matrix: characterization of new targets and tools for thrombolysis
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List of publications |
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Varjú I, Longstaff C, Szabó L, Farkas AZ, Varga-Szabó VJ, Tanka-Salamon A, Machovich R, Kolev K: DNA, histones and neutrophil extracellular traps exert anti-fibrinolytic effects in a plasma environment, THROMB HAEMOSTASIS 113: (6) 1289-1298, 2015 | Longstaff C; Thelwell C; Williams S; Silva MMCG; Szabó L; Kolev K: The interplay between tissue plasminogen activator domains and fibrin structures in the regulation of fibrinolysis: kinetic and microscopic studies, Blood 117: 661-668, 2011 | Varjú I; Sótonyi P; Machovich R; Szabó L; Tenekedjiev T; Silva M; Longstaff C; Kolev K: Hindered dissolution of fibrin formed under mechanical stress, J Thromb Haemost 9: 979-986, 2011 | Rottenberger Z; Kolev K: Matrix metalloproteinases at key junctions in the pathomechanism of stroke, Cent Eur J Biol 6: 471-485, 2011 | Wohner N; Sótonyi P; Machovich R; Szabó L; Tenekedjiev K; Silva MMCG; Longstaff C; Kolev K: Lytic resistance of fibrin containing red blood cells, Arterioscl Thromb Vasc Biol 31: 2306-2313, 2011 | Wohner N; Kovács A; Machovich R; Kolev K: Modulation of the von Willebrand factor-dependent platelet adhesion through alternative proteolytic pathways, Thromb Res 129: e41-e46, 2012 | Tenekedjiev K; Nikolova N; Kolev K: Applications of Monte Carlo Simulation in Modelling of Biochemical Processes, Charles J Mode (Ed.) Applications of Monte Carlo Methods in Biology, Medicine and Other Fields of Science. (ISBN:978-953-307-427-6) pp. 57-76, 2011 | Kolev K; Longstaff C: Retarded tissue plasminogen activator and facilitated plasmin action in fibrin modified by carboxypeptidase B, J Thromb Haemost 10: e23-e24, 2012 | Kolev K; Rottenberger Z; Komorowicz E; Szabó L; Machovich R: Fibrinolysis at the interface of blood vessel wall and thrombi, J Thromb Haemost 10: e21, 2012 | Longstaff C; Varju I; Szabo L; Thelwell C; Kolev K: The effect of DNA and histones on fibrin structure and the regulation of plasminogen activation and fibrinolysis, J Thromb Haemost 10: e18-e19, 2012 | Rottenberger Z; Komorowicz E; Szabó L; Bóta A; Varga Z; Machovich R; Longstaff C; Kolev K: Lytic and mechanical stability of clots composed of fibrin and blood vessel wall components, J Thromb Haemost 11: 529-538, 2013 | Longstaff C; Varjú I; Sótonyi P; Szabó L; Krumrey M; Hoell A; Bóta A; Varga Z; Komorowicz E; Kolev K: Mechanical stability and fibrinolytic resistance of clots containing fibrin, DNA and histones, J Biol Chem 288: 6946-6956, 2013 | Nikolova ND; Toneva-Zheynova D; Kolev K; Tenekedjiev K: Monte Carlo Statistical Tests for Identity of Theoretical and Empirical Distributions of Experimental Data, Theory and Applications of Monte Carlo Simulations, Prof. Wai Kin (Victor) Chan (Ed.), pp. 1-26, 2013 | Kovács A; Szabó L; Machovich R; Kolev K: FIBRIN SZERKEZET MÓDOSÍTÁSA KARBOXIPEPTIDÁZ B-VEL ÉS ARGININNEL: HATÁSOK A FIBRINOLÍZISRE, Hematológia-Transzfuziológia 45: 54, 2012 | Varjú I; Longstaff C; Szabó L; Thelwell C; Kolev K: DNS ÉS HISZTONOK HATÁSA A FIBRINSZERKEZETRE ÉS A FIBRINOLÍZISRE, Hematológia-Transzfuziológia 45: 73-74, 2012 | Rottenberger Z; Komorowicz E; Szabó L; Machovich R; Kolev K: ÉRFALKOMPONENSEK HATÁSA A TROMBUS STABILITÁSÁRA, Hematológia-Transzfuziológia 45: 67, 2012 | Görög A; Sillo P; Szabo L; Kolev K; Karpati S: Decreased fibrinolytic potential in transglutaminase 3 antibody positive dermatitis herpetiformis patients, JOURNAL OF INVESTIGATIVE DERMATOLOGY Volume: 133 Supplement: 1 Pages: S51-S51, 2013 | Kovacs A; Tenekedjiev K; Wohner N; Szabó L; Sótonyi P; Szelid Z; Nagy A; Szabó G; Merkely B; Kolev K: Sign and shape: correlation of clinical findings and clot ultrastructure in arterial thrombi, J Thromb Haemost 11 Suppl. 2: 1-2, 2013 | Varjú I; Kolev K; Longstaff C; Szabó L; Varga-Szabó V; Farkas AZ; Machovich R: The interplay of DNA, histones and neutrophil leukocytes with plasmin dependent lysis of plasma clots, J Thromb Haemost 11 Suppl. 2: 35, 2013 | Longstaff C; Varjú I; Sótonyi P; Szabó L; Krumrey M; Hoell A; Bóta A; Varga Z; Komorowicz E; Kolev K: The effects of DNA and histones on fibrin clot structure-function and on the regulation of fibrinolysis, J Thromb Haemost 11 Suppl. 2: 45, 2013 | Varjú I; Kolev K; Keresztes Z; Pap A; Tenekedjiev K; Machovich R: Fractal kinetic models of plasmin-catalyzed dissolution, J Thromb Haemost 11 Suppl. 2: 791-2, 2013 | Kovács A; Szabó L; Longstaff C; Tenekedjiev K; Machovich R; Kolev K: Ambivalent roles of carboxypeptidase B in the lytic susceptibility of fibrin, Thromb Res 133: 80-87, 2014 | Varjú I; Kolev K: Fibrinolysis at the interface of thrombosis and inflammation – the role of neutrophil extracellular traps, Fibrinolysis and thrombolysis Edited by K. Kolev, ISBN 978-953-51-1265-5, 206 pages, Publisher: InTech, pp. 31-59, 2014 | Kolev K (szerk.): Fibrinolysis and thrombolysis, ISBN 978-953-51-1265-5, 206 pages, Publisher: InTech, 2014 | Nagy AI; Szabo GY; Sotonyi P; Bagyura ZS; Kovacs A; Kolev K; Merkely B; Szelid ZS: Correlation of clinical findings and clot ultrastructure in coronary and peripheral arterial thrombi, EUROPEAN HEART JOURNAL 34 ( Suppl. 1 ): 891-892, 2013 | KOVACS A; TENEKEDJIEV K; WOHNER N; SZABÓ L; KOVALSZKY I; SÓTONYI P; SZELID Z; NAGY A; SZABÓ G; MERKELY B; KOLEV K: Clinical determinants of arterial thrombus structure and lytic sensitivity: ultrastructural and immunohistochemical studies, 22nd Congress on Fibrinolysis and Proteolysis, Marseille, France, 2014 | Varjú I; Longstaff C; Szabó L; Varga-Szabó VJ; Farkas AZ; Kolev K: Neutrophil extracellular trap (NET) components preserve thrombin activity and exert anti-fibrinolytic effects in a plasma environment, 22nd Congress on Fibrinolysis and Proteolysis, Marseille, France, 2014 | Varjú I, Tenekedjiev K, Keresztes Z, Pap AE, Szabó L, Thelwell C, Longstaff C, Machovich R, Kolev K: Fractal Kinetic Behavior of Plasmin on the Surface of Fibrin Meshwork, BIOCHEMISTRY-US 53: (40) 6348-6356, 2014 | Kovács A, Sótonyi P, Nagy AI, Tenekedjiev K, Wohner N, Komorowicz E, Kovács E, Nikolova N, Szabó L, Kovalszky I, Machovich R, Szelid Z, Becker D, Merkely B, Kolev K: Ultrastructure and composition of thrombi in coronary and peripheral artery disease: correlations with clinical and laboratory findings, THROMB RES 135: (4) 760-766, 2015 | Gábor L Sándor, Zoltán Kiss, Zoltán I Bocskai, Krasimir Kolev, Ágnes I Takács , Éva Juhász, Kinga Kránitz, Gábor Tóth, Andrea Gyenes, Imre Bojtár, Tibor Juhász, Zoltán Z Nagy: Comparison of the Mechanical Properties of the Anterior Lens Capsule Following Manual Capsulorhexis and Femtosecond Laser Capsulotomy, J REFRACT SURG 30: (10) 660-664, 2014 | Sandor GL, Kiss Z, Bocskai ZI, Kolev K, Takacs AI, Juhasz E, Kranitz K, Toth G, Gyenes A, Bojtar I, Juhasz T, Nagy ZZ: Evaluation of the mechanical properties of the anterior lens capsule following femtosecond laser capsulotomy at different pulse energy settings., J REFRACT SURG 31: (3) 153-157, 2015 | Ecsedy M, Sandor GL, Takacs AI, Kranitz K, Kiss Z, Kolev K, Nagy ZZ: Femtosecond laser-assisted cataract surgery in Alport syndrome with anterior lenticonus., EUR J OPHTHALMOL doi: 10.5301/ejo.5000603, 2015 | Longstaff C, Kolev K: Basic mechanisms and regulation of fibrinolysis, J THROMB HAEMOST 13: S98-S105, 2015 | Bannish B, Kolev K, Longstaff C: Experimental validation of a stochastic multiscale model of fibrinolysis, J THROMB HAEMOST 13: (Suppl. 2) 337, 2015 | Kolev K: Cellular and mechanical modulators of fibrin structure, J THROMB HAEMOST 13: (Suppl. 2) 55, 2015 | Tanka-Salamon A, Komorowicz E, Szabo L, Machovich R, Kolev K: Free fatty acids modulate thrombin activity on fibrinogen and destabilise fibrin clots, J THROMB HAEMOST 13: (Suppl. 2) 838, 2015 | Varjú I, Longstaff C, Szabó L, Varga-Szabó VJ, Farkas AZ, Komorowicz E, Kolev K: Mechanisms by which DNA, histones and neutrophil extracellular traps stabilise clots towards mechanical and fibrinolytic breakdown, J THROMB HAEMOST 13: (Suppl. 2) 1-2, 2015 | Farkas AZ, Varga-Szabó VJ, Varjú I, Szabó L, Kolev K: A NEUTROFIL EXTRACELLULARIS CSAPDA (NET) KOMPONENSEI STABILIZÁLJÁK A PLAZMAALVADÉKOT, METABOLIZMUS 12: (4) 248, 2014 | Komorowicz E, Balázs N, Varga Z, Bóta A, Szabó L, Kolev K: HIALURONSAV JELENLÉTÉBEN VASTAGABB SZÁLÚ, DE A PLAZMINOGÉN/PLAZMIN RENDSZERREL SZEMBEN MÉGIS ELLENÁLLÓBB FIBRINHÁLó KELETKEZIK, METABOLIZMUS 12: (4) 252-253, 2014 | Kovács A, Tenekedjiev K, Wohner N, Szabó L, Kovalszky I, Sótonyi P, Szelid Zs, Nagy A, Szabó Gy, Merkely B, Kolev K: AZ ARTÉRIÁS TROMBUSSZERKEZET KLINIKAI DETERMINÁNSAI: ULTRASTRUKTURÁLIS ES IMMUNFLUORESZCENS MEGFIGYELÉSEK, METABOLIZMUS 12: (4) 253, 2014 | Varjú I, Longstaff C, Varga-Szabó VJ, Farkas AZ, Kolev K: A HISZTONOK KIVÉDIK A TROMBIN INAKTIVÁCIÓJÁT ÉS SEMLEGESÍTIK A HEPARIN HATÁSÁT, METABOLIZMUS 12: (4) 263, 2014 | Nagy AI, Szabo GY, Sotonyi P, Bagyura ZS, Kovacs A, Kolev K, Merkely B, Szelid ZS: Correlation of clinical findings and clot ultrastructure in coronary and peripheral arterial thrombi, EUR HEART J 34: (Suppl 1) 891-892, 2013 |
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