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Új MIO-tartalmú biokatalizátorok szerkezete és mechanizmusa
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Ezen az oldalon az NKFI Elektronikus Pályázatkezelő Rendszerében nyilvánosságra hozott projektjeit tekintheti meg.
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Közleményjegyzék |
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Dima, N. A.; Filip, A.; Bencze, L. C.; Oláh, M.; Sátorhelyi, P.; Vértessy, B. G.; Poppe,L.; Paizs,C.: Expression and purification of recombinant phenylalanine ammonia-lyase from Petroselinum crispum, Studia Universitatis Babes-Bolyai, Seria Chemia, 2016 | Varga, A.; Filip, .; Bencze, L.C.; Sátorhelyi, P.; Bell, E.; Vértessy, B.G.; Poppe, L.; Paizs, C.: Expression and purification of recombinant phenylalanine 2,3-aminomutase from Pantoea agglomerans, Studia Universitatis Babes-Bolyai, Seria Chemia, 2016 | Boros, Z.; Hornyánszky, G.; Nagy, J.; Poppe, L.: From synthetic chemistry and stereoselective biotransformations to enzyme biochemistry – The Bioorganic Chemistry Group at the Budapest University of Technol. and Econ., Periodica Polytechnica Chemical Engineering 2015, 59(1), 59-71., 2015 | Bartha-Vári, J. H.; Toşa, M. I.; Irimie, F.-D.; Weiser, D.; Boros, Z.; Vértessy, B. G.; Paizs, C.; Poppe, L.: Immobilization of phenylalanine ammonia-lyase on single-walled carbon nanotubes for stereoselective biotransformations in batch and in continuous-flow modes, ChemCatChem, 2015, 7(7), 1122-1128., 2015 | Weiser, D.; Bencze L. C.; Bánóczi, G.; Ender, F.; Kókai, E.; Szilágyi, A.; Vértessy, B. G.; Farkas, Ö; Paizs, C.; Poppe, L.: Phenylalanine ammonia-lyase catalyzed deamination of an acyclic amino acid - Enzyme mechanistic studies aided by a novel microreactor filled with magnetic nanoparticles, ChemBioChem 2015, 16(16), 2283-2288., 2015 | Bánóczi, G.; Szabó, C.; Bata, Z.; Filip, A.; Hornyánszky, G; Poppe, L.: Structural modeling of phenylalanine ammonia-lyases and related mio-containing enzymes – an insight into thermostability and ionic interactions, Studia Universitatis Babes-Bolyai, Seria Chemia, 2015 | Ender, F.; Weiser, D.; Nagy, B.; Bencze L. C.; Paizs, C.; Pálovics, P.; Poppe, L.: Microfluidic multiple cell chip reactor filled with enzyme-coated magnetic nanoparticles – An efficient and flexible novel tool for enzyme catalyzed biotransformations, Journal of Flow Chemistry, 2015 | Ender, F.; Weiser, D.; Vitéz, A.; Sallai, G.; Németh, M.; Poppe, L: In-situ measurement of magnetic nanoparticle quantity in a microfluidic device, Microsystems Technology, 2015 | Bencze, L. C.; Komjáti, B.; Pop, L. A.; Paizs, C.; Irimie, F.-D.; Nagy, J.; Poppe, L.; Toşa, M. I.:: Synthesis of enantiopure L-(5-phenylfuran-2-yl)alanines by a sequential multienzyme process, Tetrahedron:Asymmetry 2015, 26, 1095-1101., 2015 | Weiser, D.; Varga, A.; Kovács, K.; Nagy, F.; Szilágyi, A.; Vértessy, B. G.; Paizs, C.; Poppe, L.: Bisepoxide Cross-Linked Enzyme Aggregates – Novel Immobilized Biocatalysts for Selective Biotransformations, ChemCatChem, 2014 | Varga, A.; Nagy, B.; Miklós, M.; Irimie, F. D.; Poppe, L.; C Paizs, C.: Stereoselectivity of PAL under non-optimal conditions, Protein Science, 2015, 24, 55-56 (29th Annual Symposium of the Protein Society, 22-25 July, 2015, Barcelona, Spain), 2015 | Poppe, L.; Weiser, D.; Ender, F.; Bartha-Vári, H.; Paizs, C.; Vértessy, B. G.: Nanosupported phenylalanine ammonia-lyase in microreactors, 3rd International Conference Implementation of Microreactor Technology in Biotechnology – IMTB 2015. május 10-13, Opatija, Horvátország., 2015 | Boros, Z.; Weiser, D.; Ender, F.; Bartha-Vári, H.; Oláh, M.;, Falus, P.; Paizs, C.; Vértessy, B.G.; Servi, S.; Poppe, L.: Immobilized enzymes in microfluidic systems – phenylalanine ammonia-lyase-, lipase- and protease-catalyzed processes., Biotrans 2015, 12th International Symposium on Biocatalysis. 2015. július 26-30, Bécs, Ausztria., 2015 | Weiser, D.; Varga, A.; Kovács, K.; Nagy, F.; Szilágyi, A.; Vértessy, B. G.; Paizs, C.; Poppe, L.: Bisepoxide Cross-Linked Enzyme Aggregates – Novel Immobilized Biocatalysts for Selective Biotransformations, ChemCatChem, 2014 | Boros, Z.; Hornyánszky, G.; Nagy, J.; Poppe, L.: From synthetic chemistry and stereoselective biotransformations to enzyme biochemistry – The Bioorganic Chemistry Group at the Budapest University of Technol. and Econ., Per. Polytechn. Chem. Eng., 2014 | Bata Z., Kovács K., Vértessy G. B., Poppe L.: Aromás aminosav C-N-liáz és 2,3-aminomutáz enzimek vizsgálata, MKE Vegyészkonferencia. 2013. június 26-28, Hajdúszoboszló, Magyarország, 2013 | Kókai E., Kovács K., Weiser D., Vértessy B.G., Poppe L., Nagy J.: Vizsgálatok nem-természetes alfa- és béta aminosavak előállításához., Vegyészkonferencia. 2013. június 26-28, Hajdúszoboszló, Magyarország, 2013 | Poppe L., Pilbák S., Farkas Ö., Kovács K., Bánóczi G., Weiser D., Boros Z., Vértessy B. G., Paizs C.: MIO-containing ammonia-lyases and 2,3-aminomutases – Mechanism, immobilization and biotransformations in batch and continuous-flow systems, Biotrans 2013, 11th International Symposium on Biocatalysis. 2013. július 21-25, Manchester, Egyesült Királyság, 2013 | Filip, A.; Bartha-Vári, J. H.; Bánóczy, G.; Poppe, L.; Paizs, C., Irimie, F. D.: Non-natural amino acids via the MIO-enzyme toolkit, Protein Science, 2015, 24, 54-55 (29th Annual Symposium of the Protein Society, 22-25 July, 2015, Barcelona, Spain), 2015 | Weiser D., Kovács K., Ender F., Vértessy B .G., Poppe L.: Enzyme coated sol-gel nanoparticles for use in continuous flow microfluidical devices, XVII International Sol-Gel Conference. 2013. augusztus 25-30, Madrid, Spanyolország, 2013 | Boros Z., Abaházi E., Oláh M., Nagy-Győr L., Falus P., Bódai V., Sátorhelyi P., Erdélyi B., Kovács K., Weiser D., Vértessy B. G., Poppe L.: Immobilized enzymes for biotransformations in continuous-flow systems, 4th Conferences on Frontiers in Organic Synthesis Technology. 2013. október 16-18, Budapest, Magyarország, 2013 | Bencze, L. C.; Filip, A.; Bánóczi, G.; Toşa, M. I. Irimie, F. D.; Poppe, L.; Paizs, C.: Styryl-alanines as novel substrates for phenylalanine ammonia lyase, International Symposium on Synthesis and Catalysis, 2-4 September, 2015. Evora, Portugal. (poster, awarded with the runner-up prize for Catalysis), 2015 | Bata, Z.; Bánóczi, G.; Kovács, K.; Vértessy, B. G.; Paizs, C.; Poppe, L.: Homology modelling of MIO-dependent ammonia-lyases and 2,3-aminomutases - Mechanistic comparisons, Env. Eng. Manag. J., 2013 | Varga, A.; Zaharia, V.; Nógrádi, M.; Poppe, L.: Chemoenzymatic synthesis of both enantiomers of 3-hydroxy- and 3-amino-3-phenylpropanoic acid, Tetrahedron:Asymmetry, 2013 | Weiser, D.; Bencze, L. C.; Paizs, C.; Poppe, L.; Ender, F.: Magne-Chip: an efficient tool for screening of selective biotransformations, 5th Conferences on Frontiers in Organic Synthesis Technology. 21-23 October, 2015, Budapest, Hungary., 2015 | Poppe, L.: Enzyme immobilization – A tool to improve biocatalysts., COST „Systems Biocatalysis” Training School Conference, 2014 | Kovács, K.; Bánóczi, G.; Varga, A.; Szabó, I.; Holczinger, A.; Hornyánszky, G.; Zagyva, I.; Paizs, C.; Vértessy, B. G.; Poppe, L.: Expression and properties of the highly alkalophilic phenylalanine ammonia-lyase of thermophilic Rubrobacter xylanophilus, PLoS ONE, 2014 | Poppe, L.; Paizs, C.; Vértessy, B. G.; Kovács, K.; Weiser, D.; Varga, A.; Vári, H.; Bánóczi, G.; Bell, E.; Kókai, E.; Boros, Z.: MIO-enzymes – Novel enzymes, immobilization methods and applications, 4th International Conference on Novel Enzymes. 2014. október 14-17, Gent, Belgium, 2014 | Ender, F.; Weiser, D.; Vitéz, A.; Poppe, L.: Enzyme Coated Magnetic Nanoparticles For Use In Continuous Flow Microfluidic Devices, Lab-on-a-Chip European Congress, 2014. március 10-11, Berlin, Németország, 2014 | Bánóczi, G.; Bata, Z.; Hornyánszky, G.; Poppe, L.; Farkas, Ö.; Héberger, K.: Enzyme-substrate interactions in Burkholderia sp HME13 ergothionase - Ab initio prediction of the binding pose and mechanism using bioinformatics, Schrödinger Hungarian User Group Meeting, 25 November, 2014, Budapest, Hungary, 2014 |
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