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Fémionok által vezérelt fehérje-DNS kölcsönhatás: fémion-függő molekulák potenciális alkalmazási lehetőségekkel
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R.K. Balogh, B. Gyurcsik, M. Jensen, P.W. Thulstrup, U. Köster, N.J. Christensen, F.J. Mørch, M.L. Jensen, A. Jancsó, L. Hemmingsen: Flexibility of the CueR Metal Site Probed by Instantaneous Change of Element and Oxidation State from AgI to CdII, Chem. Eur. J., 26, 7451–7457 (2020). DOI: 10.1002/chem.202000132, 2020 | R.K. Balogh, E. Németh, N.C. Jones, S.Vr Hoffmann, A. Jancsó, B. Gyurcsik: A study on the secondary structure of the metalloregulatory protein CueR: effect of pH, metal ions and DNA, Eur. Biophys. J., 2020, benyújtva, 2021 | B. Hajdu, R. Csáki, K. Kato, K. Nagata, B. Gyurcsik: Novel zinc finger-based artifical nucleases, ARBRE-MOBIEU Plenary Meeting, February 24-26, 2020, Prague, Czech Republic, 2020 | H.A.E.H. Abd Elhameed, D. Ungor, N. Igaz, M.K. Gopisetty, M. Kiricsi, E. Csapó, B. Gyurcsik: High molecular weight PEI-based water-soluble lipopolymer for transfection of cancer cells, Macromol. Biosci., 2000040 (2020). DOI:10.1002/mabi.202000040, 2020 | A. Jancsó, J.G. Correia, D. Szunyogh, R.K. Balogh, J. Schell, M.L. Jensen, P.W. Thulstrup, L. Hemmingsen: A reference compound for 199mHg PAC spectroscopy, Nucl. Instrum. Methods Phys. Res. A, 2020, benyújtva., 2021 | Nemeth E, Balogh RK, Borsos K, Czene A, Thulstrup PW, Gyurcsik B: Intrinsic protein disorder could be overlooked in cocrystallization conditions: An SRCD case study, PROTEIN SCI 25: (11) 1977-1988; DOI: 10.1002/pro.3010, 2016 | Németh E, Asaka MN, Kato K, Fábián Z, Oostenbrink C, Christensen HEM, Nagata K, Gyurcsik B: Chemical approach to biological safety - Molecular level control of an integrated zinc finger nuclease, ChemBioChem., 19, 66–75 (2018)., 2018 | A. Belczyk-Ciesielska, B. Csipak, B. Hajdu, A. Sparavier, M.N. Asaka, K. Nagata, B. Gyurcsik, W. Bal: Nickel(II)-promoted specific hydrolysis of zinc finger proteins., Metallomics, 10, 1089–1098 (2018), 2018 | Chakraborty S, Pallada S, Pedersen JT, Jancso A, Correia JG, Hemmingsen L: Nanosecond Dynamics at Protein Metal Sites: An Application of Perturbed Angular Correlation (PAC) of gamma‑Rays Spectroscopy, Acc. Chem. Res., 56 (9) 2225-2232 (2017); DOI: 10.1021/acs.accounts.7b00219, 2017 | Mesterházy E, Boff B, Lebrun C, Delangle P, Jancsó A: Oligopeptide models of the metal binding loop of the bacterial copper efflux regulator protein CueR as potential Cu(I) chelators, Inorg. Chim. Acta 472, 192-198 (2018)., 2018 | Fábián Z, Németh E, Gyurcsik B: Structural activation of NColE7-based artificial metallonucleases, XXVI. International Conference on Coordination and Bioinorganic Chemistry, Smolenice, Slovakia, June 4-9 (2017), 2017 | Gyurcsik B: Studying protein interactions through their metal ion binding properties by CD spectroscopy, XXVI. International Conference on Coordination and Bioinorganic Chemistry, Smolenice, Slovakia, June 4-9 (2017), 2017 | L.I. Szekeres, B. Gyurcsik, T. Kiss, Z. Kele, A. Jancso: Interaction of arsenous acid with the dithiol-type chelator British Anti-Lewisite (BAL): Structure and stability of species formed in an unexpectedly complex system., Inorg. Chem., 57, 7191–7200 (2018)., 2018 | E. Mesterházy, C. Lebrun, A. Jancsó, P. Delangle: A Constrained Tetrapeptide as a Model of Cu(I) Binding Sites Involving Cu4S6 Clusters in Proteins, Inorg. Chem., 57, 5723–5731 (2018)., 2018 | E. Mesterházy, C. Lebrun, S. Crouzy, A. Jancsó, P. Delangle: Short oligopeptides with three cysteine residues as models of sulphur-rich Cu(I)- and Hg(II)-binding sites in proteins, Metallomics, 10 (9) 1232-1244 (2018), 2018 | H.A.H. Abd Elhameed, B. Hajdu, R.K. Balogh, E. Hermann, É. Hunyadi-Gulyás, B. Gyurcsik: Purification of proteins with native terminal sequences using a Ni(II)-cleavable C-terminal hexahistidine affinity tag, Protein Exp. Pur., 159, 53–59 (2019). DOI: 10.1016/j.pep.2019.03.009, 2019 | L.I. Szekeres, S. Bálint, G. Galbács, I. Kálomista, T. Kiss, F.H. Larsen, L. Hemmingsen, A. Jancsó: Hg2+ and Cd2+ binding of a bioinspired hexapeptide with two cysteine units constructed as a minimalistic metal ion sensing fluorescent probe, Dalton Trans., 48 (2019) 8327-8339. DOI: 10.1039/c9dt01141b, 2019 | R.K. Balogh, B. Gyurcsik, E. Hunyadi-Gulyás, J. Schell, P.W. Thulstrup, L. Hemmingsen, A. Jancsó: C-terminal cysteines of CueR act as auxiliary metal site ligands upon HgII binding - a mechanism to prevent transcriptional activation by divalent metal ions?, Chem. Eur. J., 25, 15030–15035 (2019). DOI: 10.1002/chem.201902940, 2019 | Heba A.H. Abd Elhameed, Bálint Hajdu, Attila Jancsó, Albert Kéri, Gábor Galbács, Béla Gyurcsik: Modulation of the catalytic activity of a metallonuclease by tagging with oligohistidine, J. Inorg. Biochem., 206, 111013 (2020). DOI:10.1016/j.jinorgbio.2020.111013, 2020 | H.A.H. Abd Elhameed, B. Hajdu, R.K. Balogh, E. Hermann, É. Hunyadi-Gulyás, B. Gyurcsik: Purification of proteins with native terminal sequences using a Ni(II)-cleavable C-terminal hexahistidine affinity tag, Protein Exp. Pur., 159, 53–59 (2019). DOI: 10.1016/j.pep.2019.03.009, 2019 | L.I. Szekeres, S. Bálint, G. Galbács, I. Kálomista, T. Kiss, F.H. Larsen, L. Hemmingsen, A. Jancsó: Hg2+ and Cd2+ binding of a bioinspired hexapeptide with two cysteine units constructed as a minimalistic metal ion sensing fluorescent probe, Dalton Trans., 48 (2019) 8327-8339. DOI: 10.1039/c9dt01141b, 2019 | R.K. Balogh, B. Gyurcsik, E. Hunyadi-Gulyás, J. Schell, P.W. Thulstrup, L. Hemmingsen, A. Jancsó: C-terminal cysteines of CueR act as auxiliary metal site ligands upon HgII binding - a mechanism to prevent transcriptional activation by divalent metal ions?, Chem. Eur. J. accepted (2019). DOI: 10.1002/chem.201902940, 2019 | H.A.H Abd Elhameed, B. Hajdu, E. Hermann, M.K. Goppisetty, M. Kiricsi, D.A. Ungor, E. Csapó, W. Bal, B. Gyurcsik: Metal ions as regulatory elements of artificial nucleases, ISMEC2019, International Symposium on Metal Complexes, 2019 | H.A.H Abd Elhameed, B. Hajdu, E. Hermann, M.K. Goppisetty, M. Kiricsi, D.A. Ungor, E. Csapó, W. Bal, B. Gyurcsik: Metal ions as regulatory elements of artificial nucleases, ISMEC2019, International Symposium on Metal Complexes, 11-14 June 2019, Debrecen, Hungary, 2019 | E. Hermann, H.A.H. Abd Elhameed, E. Németh, R. Csáki, B. Hajdu, B. Gyurcsik: Purification and characterization of the C45-ZF-N85 artificial zinc-finger nuclease and its mutants, XXVII. International Conference on Coordination and Bioinorganic Chemistry (XXVII. ICCBIC), June 2-7, 2019, Smolenice, Slovakia., 2019 | B. Hajdu, H.A.H. Abd Elhameed, E. Hermann, R.K. Balogh, É. Hunyadi-Gulyás, K. Kato, K. Nagata, W. Bal, B. Gyurcsik: Applications of Ni(II)-induced peptide bond cleavage, 19th International Conference on Biological Inorganic Chemistry (ICBIC-19), August 11-16 2019, Interlaken, Switzerland, 2019 | Heba A.H. Abd Elhameed1, Bálint Hajdu, Attila Jancsó, Albert Kéri, Gábor Galbács, Béla Gyurcsik: Modulation of the catalytic activity of a metallonuclease by tagging with oligohistidine, J. Inorg. Biochem: JINORGBIO_2019_546 - benyújtott közlemény, 2019 | Nemeth E, Balogh RK, Borsos K, Czene A, Thulstrup PW, Gyurcsik B: Intrinsic protein disorder could be overlooked in cocrystallization conditions: An SRCD case study, PROTEIN SCI 25: (11) 1977-1988; DOI: 10.1002/pro.3010, 2016 | Tóth EN, May NV, Rockenbauer A, Peintler G, Gyurcsik B: Exploring the boundaries of direct detection and characterization of labile isomers – a case study of copper(II)–dipeptide systems, Dalton Trans., 46, 8157–8166 (2017). DOI: 10.1039/C7DT00884H, 2017 | Németh E, Asaka MN, Kato K, Fábián Z, Oostenbrink C, Christensen HEM, Nagata K, Gyurcsik B: Chemical approach to biological safety - Molecular level control of an integrated zinc finger nuclease, ChemBioChem., accepted manuscript (2017), 2017 | Belczyk-Ciesielska A, Csipak B, Hajdu B, Sparavier A, Asaka MN, Nagata K, Gyurcsik B, Bal W: The zinc finger units lacking sensitive sequences are unaffected during nickel(II)-promoted hydrolysis of ZF proteins., J. Inorg. Biochem, submitted manuscript (2016) - JINORGBIO_2016_113, 2017 | Chakraborty S, Pallada S, Pedersen JT, Jancso A, Correia JG, Hemmingsen L: Nanosecond Dynamics at Protein Metal Sites: An Application of Perturbed Angular Correlation (PAC) of gamma‑Rays Spectroscopy, Acc. Chem. Res., 56 (9) 2225-2232 (2017); DOI: 10.1021/acs.accounts.7b00219, 2017 | Mesterházy E, Boff B, Lebrun C, Delangle P, Jancsó A: Oligopeptide models of the metal binding loop of the bacterial copper efflux regulator protein CueR as potential Cu(I) chelators, Inorg. Chim. Acta (2017), Article in Press DOI: 10.1016/j.ica.2017.06.062., 2017 | Fábián Z, Németh E, Gyurcsik B: Structural activation of NColE7-based artificial metallonucleases, XXVI. International Conference on Coordination and Bioinorganic Chemistry - Modern trends in coordination, bioinorganic, and applied inorganic chemistry, Smolenice, Slova, 2017 | Gyurcsik B: Studying protein interactions through their metal ion binding properties by CD spectroscopy, XXVI. International Conference on Coordination and Bioinorganic Chemistry - Modern trends in coordination, bioinorganic, and applied inorganic chemistry, Smolenice, Slova, 2017 | Szekeres L, Gyurcsik B, Kiss T, Hoffmann SV, Jones NC, Jancsó A: AsIII-binding of a peptide bearing two cysteine residues, 14th International Symposium on Applied Bioinorganic Chemistry – ISABC- ISABC14, Toulouse, France, June 07-10, 2017, 2017 | Szekeres L, Gyurcsik B, Kiss T, Hoffmann SV, Jones NC, Jancsó A: Synergistic effects observed in the AsIII-binding of small ligands possessing multiple thiol groups, 14th International Symposium on Applied Bioinorganic Chemistry – ISABC- ISABC14, Toulouse, France, June 07-10, 2017, 2017 | Balogh RK, Jancsó A, Gyurcsik B, Németh E: pH induced structural switch of CueR metalloregulatory protein, 9th International Union of Pure and Applied Biology (IUPAB) Congress and 11th European Biophysical Societies' Association (EBSA) Congress, Edinburgh, Scotland, 2017., 2017 | Hermann E, Gyurcsik B, Wéber E: Az N-terminális aminosavak lehetséges szerépenek megismerése az NColE7 metallonukleázban, XL. Kémiai Előadói Napok, 2017. október 16-18, Szeged, 2017 | Tóth EN, May NV, Rockenbauer A, Peintler G, Gyurcsik B: Exploring the boundaries of direct detection and characterization of labile isomers – a case study of copper(II)–dipeptide systems, Dalton Trans., 46, 8157–8166 (2017). DOI: 10.1039/C7DT00884H, 2017 | Németh E, Asaka MN, Kato K, Fábián Z, Oostenbrink C, Christensen HEM, Nagata K, Gyurcsik B: Chemical approach to biological safety - Molecular level control of an integrated zinc finger nuclease, ChemBioChem., 19, 66–75 (2018)., 2018 | A. Belczyk-Ciesielska, B. Csipak, B. Hajdu, A. Sparavier, M.N. Asaka, K. Nagata, B. Gyurcsik, W. Bal: Nickel(II)-promoted specific hydrolysis of zinc finger proteins., Metallomics, 10, 1089–1098 (2018), 2018 | Mesterházy E, Boff B, Lebrun C, Delangle P, Jancsó A: Oligopeptide models of the metal binding loop of the bacterial copper efflux regulator protein CueR as potential Cu(I) chelators, Inorg. Chim. Acta 472, 192-198 (2018)., 2018 | L.I. Szekeres, B. Gyurcsik, T. Kiss, Z. Kele, A. Jancso: Interaction of arsenous acid with the dithiol-type chelator British Anti-Lewisite (BAL): Structure and stability of species formed in an unexpectedly complex system., Inorg. Chem., 57, 7191–7200 (2018)., 2018 | E. Mesterházy, C. Lebrun, A. Jancsó, P. Delangle: A Constrained Tetrapeptide as a Model of Cu(I) Binding Sites Involving Cu4S6 Clusters in Proteins, Inorg. Chem., 57, 5723–5731 (2018)., 2018 | E. Mesterházy, C. Lebrun, S. Crouzy, A. Jancsó, P. Delangle: Short oligopeptides with three cysteine residues as models of sulphur-rich Cu(I)- and Hg(II)-binding sites in proteins, Metallomics, 10 (9) 1232-1244 (2018), 2018 | R.K. Balogh, E.Mesterházy, B. Gyurcsik, A. Jancsó, K. Kato, K. Nagata: Detection of toxic metal ions by the CueR metalloregulator, EUROBIC Birmingham, UK, 2018., 2018 | Hermann E., Czene A., Wéber E., Hetényi A., Martinek T., Gyurcsik B: NColE7 és C127 fehérjék szerkezetének NMR spektroszkópiás vizsgálata, 52. Komplexkémiai Kollokvium, 2018 | Heba Abd Elhameed, Balint Hajdu, Zita Fabian, Eniko Hermann, Wojtek Bal, Bela Gyurcsik: Affinity protein purification resulting in protein sequence without remaining amino acid residues, COST conference, 2018.03.19-21., Warsaw, Poland, 2018 | Balogh Ria Katalin: Transcriptional activator CueR protein: purification, characterization and potential bioanalytical application, SZTE Doktori Repozitórium, 2020 | Heba Alaa Eldeen Hosiny Abd Elhameed: Artificial metallonucleases - molecular tools for gene therapy of cancer, SZTE Doktori Repozitórium, 2020 | Jancsó, Attila ; Correia, Joao G. ; Balogh, Ria K. ; Schell, Juliana ; Jensen, Marianne L. ; Szunyogh, Daniel ; Thulstrup, Peter W. ; Hemmingsen, Lars: A reference compound for 199m Hg perturbed angular correlation of γ -rays spectroscopy, Nuclear Inst. and Methods in Physics Research, A 1002 (2021) 165154, 2021 | R.K. Balogh, E. Németh, N.C. Jones, S.Vr Hoffmann, A. Jancsó, B. Gyurcsik: A study on the secondary structure of the metalloregulatory protein CueR: effect of pH, metal ions and DNA, Eur. Biophys. J., 50 pp. 491-500 (2021), 2021 |
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