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Ezen az oldalon az NKFI Elektronikus Pályázatkezelő Rendszerében nyilvánosságra hozott projektjeit tekintheti meg.
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Mihalik, Á. és Csermely, P.: Heat shock partially dissociates the overlapping modules of the yeast protein-protein interaction network: a systems level model of adaptation, PLoS Comput. Biol. 7, e1002187, 2011 | Nussinov, R., Tsai, C.-J. és Csermely, P.: Allo-network drugs: harnessing allostery in cellular networks, Trends in Pharmacol. Sci. 32, 686-693, címlapsztori, 2011 | Arslan, M.A., Chikina, M. Csermely, P. és Sőti, C.: Misfolded proteins inhibit proliferation and promote stress-induced death in SV40-transformed mammalian cells, FASEB J. 26, 766-777, 2012 | Spiró, Z. Arslan, M.A., Somogyvári, M., Nguyen, M.T., Smolders, A., Dancsó, B., Németh, N., Elek, Z., Braeckman, B., Csermely, P. és Sőti, C.: RNA interference links oxidative stress to the inhibition of heat stress adaptation, Antiox. Redox Signaling. 17, 890-901, 2012 | Papp, D., Csermely, P. és Sőti, C.: A role for SKN-1/Nrf in pathogen resistance and immunosenescence in Caenorhabditis elegans, PLoS Pathogens, 8, e1002673, 2012 | Papp, D, Lenti, K., Módos, D., Fazekas, D., Dúl, Z., Türei, D., Földvári-Nagy, L., Nussinov, R., Csermely, P. és Korcsmáros, T.: The NRF2-related interactome and regulome contain multifunctional proteins and fine-tuned autoregulatory loops, FEBS Letters 586, 1795-1802, 2012 | Szalay-Bekő, M., Palotai, R., Szappanos, B., Kovács, I.A., Papp, B. és Csermely, P.: ModuLand plug-in for Cytoscape: determination of hierarchical layers of overlapping modules and community centrality, Bioinformatics 28, 2202-2204, 2012 | Farkas, I.J., Korcsmáros, T., Kovács, I.A., Mihalik, Á., Palotai, R., Simkó, G.I., Szalay, K.Z., Szalay-Bekő, M., Vellai, T., Wang, S. és Csermely, P.: Network-based tools in the identification of novel drug-targets, Science Signaling 4, pt3, 2011 | Csermely, P., Sandhu, K.S., Hazai, E., Hoksza, Z., Kiss, H.J.M., Miozzo, F. Veres, D.V., Piazza, F. és Nussinov, R: Disordered proteins and network disorder in network representations of protein structure, dynamics and function. Hypotheses and a comprehensive review, Curr. Prot. Pept. Sci. 13, 19-33, 2012 | Gáspár, E.M. és Csermely, P: Rigidity and flexibility of biological networks, Briefings Funct. Genomics 11, 443-456, 2012 | Hegedus, T., Gyimesi, G., Gáspár, E.M., Szalay, K.Z., Gangal, R. és Csermely, P: Potential application of network descriptions for understanding conformational changes and protonation states of ABC transporters, Curr. Pharm. Des. 19, 4155-4172, 2013 | Gyurkó, D., Sőti, C., Steták, A. és Csermely, P: System level mechanisms of adaptation, learning, memory formation and evolvability: the role of chaperone and other networks, Curr. Prot. Pept. Sci. 14, nyomtatás alatt, 2013 | Sandhu, K. S., Li, G., Poh, H. M., Quek, Y. L., K., Sia, Y. Y., Peh, S. Q., Mulawadi, F. H., Lim, J., Zhang, J., Sikic, M., Menghi, F., Thalamuthu, A., Sung, W. K., Ruan, X., Fullwood, M. J., Liu, E. Csermely, P. Ruan, J.: Large scale functional organization of long-range chromatin interaction networks, Cell Reports, 2, 1207-1219, 2012 | Bozoky, B., Savchenko, A., Csermely, P., Korcsmaros, T., Dul, Z., Ponten, F., Szekely, L. and Klein, G.: Novel signatures of cancer associated fibroblasts, Intl. J. Cancer 133, 286-294, 2013 | Csermely, P.: The appearance and promotion of creativity at various levels of interdependent networks, Talent Development Excellence, 5, 115-123, 2013 | Csermely, P., Korcsmáros, T., Kiss, H.J.M., London, G. and Nussinov, R.: Structure and dynamics of biological networks: a novel paradigm of drug discovery. A comprehensive review, Pharmacol. Therap. 138, 333-408, 2013 | Szilágyi, A., Nussinov, R. and Csermely P.: Allo-network drugs: extension of the allosteric drug concept to protein-protein interaction and signaling networks, Curr. Top. Med. Chem. 13, 64-77, 2013 | Csermely P. Nussinov, R. and Szilágyi, A.: From allosteric drugs to allo-network drugs: State of the art and trends of design, synthesis, and computational methods, Curr. Top. Med. Chem. 13, 1-4, 2013 | Fazekas, D. Koltai, M., Türei, D., Módos, D., Pálfy, M., Dúl, Z., Zsákai, L., Szalay-Bekő, M., Lenti, K., Farkas, I.J., Vellai, T., Csermely, P. and Korcsmáros, T.: SignaLink 2 – A signaling pathway resource with multi-layered regulatory networks, BMC Systems Biology 7, 7, 2013 | Türei, D., Papp, D., Fazekas, D., Földvári-Nagy, L., Módos, D., Lenti, K., Csermely, P. and Korcsmaros, T.: NRF2-ome, an integrated web resource to discover protein interaction and regulatory networks of NRF2, Oxidative Medicine and Cellular Longevity, 737591, 2013 | Korcsmaros, T. Dunai, Z.A., Vellai, T. and Csermely, P.: eaching the bioinformatics of signaling networks - an integrated approach to facilitate multidisciplinary learning, Briefings Bioinformatics, nyomtatás alatt, 2013 | Simko, G.I. és Csermely, P.: Nodes having a major influence to break cooperation define a novel centrality measure: game centrality, PLoS ONE 8, e67159, 2013 | Szalay, K. Z. and Csermely, P.: Perturbation centrality: a novel centrality measure obtained by the general network dynamics tool, Turbine, preprint: http://arxiv.org/abs/1305.2496, 2013 | Nussinov, R., Ma, B., Tsai, C-J and Csermely, P.: Allosteric conformational barcodes direct signaling in the cell, Structure, in press, 2013 | Gyurko, D.M., Veres, D.V., Modos, D., Lenti, K., Korcsmaros, T. and Csermely, P.: Adaptation and learning of molecular networks as a description of cancer development at the systems-level: Potential use in anti-cancer therapies, Seminars in Cancer Biology, nyomtatás alatt, 2013 | Kubisch, J., Türei, D., Földvári-Nagy, L., Dunai, Z.A., Zsákai, L., Varga, M., Vellai, T., Csermely, P. and Korcsmáros, T.: Complex regulation of autophagy in cancer – integrated approaches to discover the networks that hold a double-edged sword, Seminars in Cancer Biology, nyomtatás alatt, 2013 | Csermely, P., Korcsmáros T.: Cancer-related networks: a help to understand, predict and change malignant transformation, Seminars in Cancer Biology, nyomtatás alatt, 2013 | Nguyen, M. T., Csermely, P. és Sőti, C.: Hsp90 chaperones PPARγ and regulates differentiation and survival of 3T3-L1 adipocytes, Cell Death Diff. 20, 1654-1663, 2013 | Korcsmaros, T. Dunai, Z.A., Vellai, T. and Csermely, P.: eaching the bioinformatics of signaling networks - an integrated approach to facilitate multidisciplinary learning, Briefings Bioinformatics 14, 618-632, 2013 | Szalay, K. Z. and Csermely, P.: Perturbation centrality and Turbine: a novel centrality measure obtained using a versatile network dynamics tool, PLoS ONE 8, e78059, 2013 | Nussinov, R., Ma, B., Tsai, C-J and Csermely, P.: Allosteric conformational barcodes direct signaling in the cell, Structure 21, 1509-1521, 2013 | Gyurko, D.M., Veres, D.V., Modos, D., Lenti, K., Korcsmaros, T. and Csermely, P.: Adaptation and learning of molecular networks as a description of cancer development at the systems-level: Potential use in anti-cancer therapies, Seminars in Cancer Biology 23, 262-269, 2013 | Kubisch, J., Türei, D., Földvári-Nagy, L., Dunai, Z.A., Zsákai, L., Varga, M., Vellai, T., Csermely, P. and Korcsmáros, T.: Complex regulation of autophagy in cancer – integrated approaches to discover the networks that hold a double-edged sword, Seminars in Cancer Biology 23, 252-261, 2013 | Csermely, P., Korcsmáros T.: Cancer-related networks: a help to understand, predict and change malignant transformation, Seminars in Cancer Biology 23, 209-212, 2013 | Gyurkó, D., Sőti, C., Steták, A. és Csermely, P.: System level mechanisms of adaptation, learning, memory formation and evolvability: the role of chaperone and other networks, Curr. Prot. Pept. Sci. 15, 171-188, 2014 | Szalay, K.Z., Nussinov, R. és Csermely, P.: Attractor structures of signaling networks: Consequences of different conformational barcode dynamics and their relations to network-based drug design, Molecular Informatics 33, 463-468, 2014 | Csermely, P., Hódsági, J., Korcsmáros, T., Módos, D., Perez-Lopez, A.R., Szalay, K., Veres, D.V., Lenti, K., Wu, L.Y. és Zhang, X.S.: Cancer stem cells display extremely large evolvability: alternating plastic and rigid networks as a potential mechanism. Network models, novel therapeutic target strategi, Seminars in Cancer Biology, nyomtatás alatt, 2014 | Földvári-Nagy, L., Ari, E., Csermely, P., Korcsmáros, T. és Vellai, T.: Starvation-response may not involve Atg1-dependent autophagy induction in nonunikont parasites, Scientific Reports 4, 5829, 2014 | Csermely, P., London, A., Wu, L.-Y. és Uzzi, B.: Structure and dynamics of core-periphery networks, J. Complex Networks 1, 93-123, 2013 | Gershenson, C., Csermely, P., Erdi, P., Hofkirchner, W., Knyazeva, H, Laszlo, A. és Thurner, S.: The past, present and future of cybernetics and systems research, Systems 1, 4-13, 2013 | Csermely, P., Mihalik, A., Vassy, Z. és London, A.: Crisis responses and crisis management: What can we learn from biological networks?, Systema 2, 23-27, 2014 | Csermely, P., Hódsági, J., Korcsmáros, T., Módos, D., Perez-Lopez, A.R., Szalay, K., Veres, D.V., Lenti, K., Wu, L.Y. és Zhang, X.S.: Cancer stem cells display extremely large evolvability: alternating plastic and rigid networks as a potential mechanism. Network models, novel therapeutic target strategi, Seminars in Cancer Biology 30, 42-51, 2015 | Veres, D.V., Gyurko, M.D., Thaler, B., Szalay, K., Fazekas, D., Korcsmaros, T. és Csermely, P.: ComPPI: a cellular compartment-specific database for protein-protein interaction network analysis, Nucleic Acids Res. 43, D485-D493, 2015 | Gyurkó, M. D., Steták, A., Sõti, C. és Csermely, P.: Multitarget network strategies to influence memory and forgetting: The Ras/Mapk pathway as a novel option., Mini Rev. Med. Chem. 15, 696-704, 2015 | Türei, D., Földvári-Nagy, L., Fazekas, D., Módos, D., Kubisch, J., Kadlecsik, T., Demeter, A., Lenti, K., Csermely, P., Vellai, T. és Korcsmáros, T.: Autophagy Regulatory Network – a systems-level bioinformatics resource for studying autophagy components and their regulation, Autophagy 11, 155-165, 2015 | Perez-Lopez, A. R., Szalay, K.Z., Türei, D., Módos, D., Lenti, K., Korcsmáros, T. és Csermely, P.: Targets of drugs are generally, and targets of drugs having side effects are specifically good spreaders of human interactome perturbations, Sci. Rep. 5, 10182, 2015 | Alexeyenko, A., Alkasalias, T., Pavlova, T., Szekely, L., Kashuba, V., Rundqvist, H., Wiklund, P., Egevad, L., Csermely, P., Korcsmaros, T., Guven, H. és Klein, G.: Confrontation of fibroblasts with cancer cells in vitro: gene network analysis of transcriptome changes and differential capacity to inhibit tumor growth, J. Exp. Clin. Canc. Res. 34:62, 2015 | Kovács, I.A. Mizsei, R. és Csermely P.: A unified data representation theory for network visualization, ordering and coarse-graining, Scientific Reports 5, 13786, 2015 |
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