Heat stress management of the “micromammal” S. pombe: development of a novel cellular model to explore new chaperone modulator drug candidates.

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Details of project

Identifier

135759

Type

Principal investigator

Vígh, László

Title in Hungarian

A “mikroemlős” S. pombe hősokkválaszának vizsgálata: egy új, dajkafehérje modulátor gyógyszerjelöltek vizsgálatára alkalmas sejtes modell fejlesztése.

Title in English

Heat stress management of the “micromammal” S. pombe: development of a novel cellular model to explore new chaperone modulator drug candidates.

Keywords in Hungarian

S. pombe, hősokk, membrán/lipid, trehalóz, hősokk fehérje, gyógyszerfejlesztés

Keywords in English

S. pombe, heat shock, membrane/lipid, trehalose, chaperones, drug development

Discipline

General biochemistry and metabolism (Council of Medical and Biological Sciences)	40 %
Ortelius classification: Metabolism
Lipid synthesis, modification and turnover (Council of Medical and Biological Sciences)	30 %
Biophysics (e.g. transport mechanisms, bioenergetics, fluorescence) (Council of Medical and Biological Sciences)	30 %
Ortelius classification: Molecular biophysics

Panel

Molecular and Structural Biology and Biochemistry

Department or equivalent

Institute of Biochemistry (HUN-REN Biological Research Centre Szeged)

Participants

Balogh, Gábor
Dukay, Brigitta Dóra
Dukic, Barbara
Glatz, Attila
Gombos, Imre
Gudmann, Péter
Hunya, Ákos Gábor
Péter, Mária
Török, Zsolt

Starting date

2020-09-01

Closing date

2025-02-28

Funding (in million HUF)

47.970