The role of the molecular interactions of SARS Cov-2 E protein and human SERCA pump in Ca2+ signaling

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Identifier

137610

Type

Principal investigator

Hegedűs, Tamás Zoltán

Title in Hungarian

A SARS Cov-2 E fehérje és a humán SERCA pumpa molekuláris kölcsönhatásainak vizsgálata és szerepe a Ca2+ jelátviteli folyamatokban

Title in English

The role of the molecular interactions of SARS Cov-2 E protein and human SERCA pump in Ca2+ signaling

Keywords in Hungarian

SARS Cov-2, E protein, membránfehérje komplexek, PDZ fehérje kölcsönhatás, fehérje tervezés, molekula dinamika

Keywords in English

SARS Cov-2, E protein, membrane protein complexes, PDZ protein interaction, protein design, molecular dynamics

Discipline

Computational biology (Council of Medical and Biological Sciences)	50 %
Cell biology and molecular transport mechanisms (Council of Medical and Biological Sciences)	40 %
Analysis, modelling and simulation of biological systems (Council of Medical and Biological Sciences)	10 %
Ortelius classification: Cell biology

Panel

Molecular and Structural Biology and Biochemistry

Department or equivalent

Dept. of Biophysics and Radiation Biology (Semmelweis University)

Participants

Berta, Blanka
Csizmadia, Georgina
Enyedi, Ágnes
Padányi, Rita
Szakályné Dr. Gereben, Orsolya
Tordai, Hedvig
Tyagi, Chetna

Starting date

2021-12-01

Closing date

2025-11-30

Funding (in million HUF)

48.000