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A kardioprotekcióban diagnosztikus és terápiás potenciállal bíró mikroRNS-ek azonosítása egy klinikailag releváns sertésmodellben
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Ezen az oldalon az NKFI Elektronikus Pályázatkezelő Rendszerében nyilvánosságra hozott projektjeit tekintheti meg.
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Baranyai T, Giricz Z, Varga ZV, Koncsos G, Lukovic D, Makkos A, Sárközy M, Pávó N, Jakab A, Czimbalmos C, Vágó H, Ruzsa Z, Tóth L, Garamvölgyi R, Merkely B, Schulz R, Gyöngyösi M, Ferdinandy P.: In vivo MRI and ex vivo histological assessment of the cardioprotection induced by ischemic preconditioning, postconditioning and remote conditioning in a closed-chest porcine model of reperfused acute myocardial infarction: importance of microvasculature., J Transl Med. 2017 Apr 1;15(1):67., 2017 | Pavo N, Lukovic D, Zlabinger K, Zimba A, Lorant D, Goliasch G, Winkler J, Pils D, Auer K, Jan Ankersmit H, Giricz Z, Baranyai T, Sárközy M, Jakab A, Garamvölgyi R, Emmert MY, Hoerstrup SP, Hausenloy DJ, Ferdinandy P, Maurer G, Gyöngyösi M.: Sequential activation of different pathway networks in ischemia-affected and non-affected myocardium, inducing intrinsic remote conditioning to prevent left ventricular remodeling., Sci Rep. 7:43958. doi: 10.1038/srep43958., 2017 | Giricz Z, Varga ZV, Baranyai T, Sipos P, Pálóczi K, Kittel Á, Buzás EI, Ferdinandy P.: Cardioprotection by remote ischemic preconditioning of the rat heart is mediated by extracellular vesicles., J Mol Cell Cardiol. 2014;68:75-8., 2014 | Perrino C, Barabási AL, Condorelli G, Davidson SM, De Windt L, Dimmeler S, Engel FB, Hausenloy DJ, Hill JA, Van Laake LW, Lecour S, Leor J, Madonna R, Mayr M, Prunier F, Sluijter JP, Schulz R, Thum T, Ytrehus K, Ferdinandy P.: Epigenomic and transcriptomic approaches in the post-genomic era: path to novel targets for diagnosis and therapy of the ischemic heart?, Cardiovasc Res. 2017 Apr 29. doi: 10.1093/cvr/cvx070., 2017 | Hausenloy DJ, Garcia-Dorado D, Bøtker HE, Davidson SM, Downey J, Engel FB, Jennings R, Lecour S, Leor J, Madonna R, Ovize M, Perrino C, Prunier F, Schulz R, Sluijter JPG, Van Laake LW, Vinten-Johansen J, Yellon DM, Ytrehus K, Heusch G, Ferdinandy P.: Novel targets and future strategies for acute cardioprotection: Position Paper of the European Society of Cardiology Working Group on Cellular Biology of the Heart., Cardiovasc Res. 2017 May 1;113(6):564-585., 2017 | Andreadou I, Iliodromitis EK, Lazou A, Gorbe A, Giricz Z, Schulz R, Ferdinandy P: Effect of hypercholesterolemia on myocardial function, ischemia-reperfusion injury and cardioprotection by preconditioning, postconditioning and remote conditioning, BR J PHARMACOL In press: In press, 2017 | Giricz Z, Varga ZV, Baranyai T, Sipos P, Pálóczi K, Kittel Á, Buzás EI, Ferdinandy P.: Cardioprotection by remote ischemic preconditioning of the rat heart is mediated by extracellular vesicles., J Mol Cell Cardiol. 2014;68:75-8., 2014 | Mariann Gyongyosi, Noemi Pavo, Katrin Zlabinger, Inna Sabdyusheva, Zsolt Petrasi, Ors Petnehazy, Peter Ferdinandy, Gerald Maurer: Effect Of Brief Repetitive Ischemia/Reperfusion On Myocardial Electrical Activity Visualized And Quantified By 3D Endocardial Electroanatomical Mapping, Presented at the Scientific Session of the American Heart Association, Dallas, USA, 2013 | Pavo N, Emmert MY, Giricz Z, Varga ZV, Ankersmit HJ, Maurer G, Hoerstrup SP, Ferdinandy P, Wu JC, Gyöngyösi M.: Real-time visualization of ischemic burden during repetitive ischemia/reperfusion, JACC Cardiovasc Imaging, 2014 | Csonka C, Kupai K, Bencsik P, Görbe A, Pálóczi J, Zvara A, Puskás LG, Csont T, Ferdinandy P.: Cholesterol-enriched diet inhibits cardioprotection by ATP-sensitive K+ channel activators cromakalim and diazoxide, Am J Physiol Heart Circ Physiol. 306(3):H405-13., 2014 | Csonka C, Szucs G, Varga-Orvos Z, Bencsik P, Csont T, Zvara Á, Puskás LG, Ferdinandy P: Ischemic postconditioning alters the gene expression pattern of the ischemic heart., Exp Biol Med (Maywood). 2014, 239(2):141-50., 2014 | Varga ZV, Zvara A, Faragó N, Kocsis GF, Pipicz M, Gáspár R, Bencsik P, Görbe A, Csonka C, Puskás LG, Thum T, Csont T, Ferdinandy P.: MicroRNAs associated with ischemia/reperfusion injury and cardioprotection by ischemic pre- and postconditioning: ProtectomiRs, Am J Physiol Heart Circ Physiol., 2014 | Varga ZV, Giricz Z, Bencsik P, Madonna R, Gyöngyösi M, Schulz R, Mayr M, Thum T, Puskás LG, Ferdinandy P.: Functional genomics of cardioprotection by ischemic conditioning and the influence of comorbid conditions: implications in target identification., Curr Drug Targets., 2015 | Baán JA, Varga ZV, Leszek P, Kuśmierczyk M, Baranyai T, Dux L, Ferdinandy P, Braun T, Mendler L.: Myostatin and IGF-I signaling in end-stage human heart failure: a qRT-PCR study., J Transl Med. 2015 Jan 16;13:1. doi: 10.1186/s12967-014-0365-0., 2015 | Pickard JM, Bøtker HE, Crimi G, Davidson B, Davidson SM, Dutka D, Ferdinandy P, Ganske R, Garcia-Dorado D, Giricz Z, Gourine AV, Heusch G, Kharbanda R, Kleinbongard P, MacAllister R, McIntyre C, Meybohm P, Prunier F, Redington A, Robertson NJ, Suleiman MS, Vanezis A, Walsh S, Yellon DM, Hausenloy DJ.: Remote ischemic conditioning: from experimental observation to clinical application: report from the 8th Biennial Hatter Cardiovascular Institute Workshop., Basic Res Cardiol. 2015 Jan;110(1):453., 2015 | Varga ZV, Zvara A, Faragó N, Kocsis GF, Pipicz M, Gáspár R, Bencsik P, Görbe A, Csonka C, Puskás LG, Thum T, Csont T, Ferdinandy P.: MicroRNAs associated with ischemia-reperfusion injury and cardioprotection by ischemic pre- and postconditioning: protectomiRs., Am J Physiol Heart Circ Physiol. 2014 Jul 15;307(2):H216-27., 2014 | Pavo N, Emmert MY, Giricz Z, Varga ZV, Ankersmit HJ, Maurer G, Hoerstrup SP, Ferdinandy P, Wu JC, Gyöngyösi M.: On-line visualization of ischemic burden during repetitive ischemia/reperfusion., JACC Cardiovasc Imaging. 2014 Sep;7(9):956-8., 2014 | Schulz R, Görge PM, Görbe A, Ferdinandy P, Lampe PD, Leybaert L.: Connexin 43 is an emerging therapeutic target in ischemia/reperfusion injury, cardioprotection and neuroprotection, Pharmacol Ther. 2015 Sep;153:90-106., 2015 | Madonna R, Cadeddu C, Deidda M, Giricz Z, Madeddu C, Mele D, Monte I, Novo G, Pagliaro P, Pepe A, Spallarossa P, Tocchetti CG, Varga ZV, Zito C, Geng YJ, Mercuro G, Ferdinandy P.: Cardioprotection by gene therapy: A review paper on behalf of the Working Group on Drug Cardiotoxicity and Cardioprotection of the Italian Society of Cardiology., Int J Cardiol. 2015 Jul 15;191:203-10., 2015 | Giricz Z: Are extracellular vesicles mediators of remote conditioning, European Society of Cardiology Congress 2015, 2015.08.29.- 09.02.- London, 2015 | Ferndinandy P: Role of micrornas and exosomes in cardioprotection, 11th International Congress on Coronary Artery Disease 2015.11.29.-12.02. - Florence, 2015 | Ferdinandy P: Plenary Valsalva lecture, XX National Congress of the Italian Society of Cardiovascular Research 2015.11.26-11.29.- Imola, 2015 | T. Baranyai, Z. Giricz, Z. V. Varga, G. Koncsos, M. Sárközy, H. Vágó, C. Czimbalmos, L. Tóth, B. Merkely, M. Gyöngyösi, P. Ferdinandy: Ischemic postconditioning prevents ischemia-induced acute myocardial dilation and limits cardiac edema in a clinically relevant, closed-chest pig model of acute myocardia, IX. Conference of the Hungarian Experimental and Clinical Pharmacological Society – Experimental Section Velence, Hungary, 26-28.03.2015., 2015 | T. Baranyai, Z. Giricz, Z. V. Varga, G. Koncsos, M. Sárközy, H. Vágó, C. Czimbalmos, L. Tóth, B. Merkely, M. Gyöngyösi, P. Ferdinandy: Ischemic postconditioning prevents ischemia-induced acute myocardial dilation and limits cardiac edema in a clinically relevant, closed-chest pig model of acute myocardia, Myocardial Function & Cellular Biology of the Heart Meeting 2015 Varenna, Italy, 30.04-03.05.2015., 2015 | T. Baranyai, Z. Giricz, M. Sárközy, H. Vágó, C. Czimbalmos, L. Tóth, B. Merkely, M. Gyöngyösi, P. Ferdinandy: Ischemic postconditioning prevents ischemia-induced acute myocardial dilation and limits cardiac edema in a clinically relevant, closed-chest pig model of acute myocardia, CARDIOLOGIA HUNGARICA 45:(Suppl. D) p. D21. (2015), 2015 | T. Baranyai, Z. Giricz, Z. V. Varga, G. Koncsos, M. Sárközy, H. Vágó, C. Czimbalmos, L. Tóth, B. Merkely, M. Gyöngyösi, P. Ferdinandy: Comprehensive analysis of ischemic postconditioning and remote ischemic perconditioning in a porcine model of acute myocardial infarction: variable effects on clinically, XXXIII. Annual Meeting of the International Society for Heart Research - European Section Bordeaux, France, 01-04.07.2015., 2015 | Csonka C, Szucs G, Varga-Orvos Z, Bencsik P, Csont T, Zvara Á, Puskás LG, Ferdinandy P: Ischemic postconditioning alters the gene expression pattern of the ischemic heart., Exp Biol Med (Maywood). 2014, 239(2):141-50., 2014 | Varga ZV, Giricz Z, Bencsik P, Madonna R, Gyöngyösi M, Schulz R, Mayr M, Thum T, Puskás LG, Ferdinandy P.: Functional genomics of cardioprotection by ischemic conditioning and the influence of comorbid conditions: implications in target identification., Curr Drug Targets., 2015 | Baán JA, Varga ZV, Leszek P, Kuśmierczyk M, Baranyai T, Dux L, Ferdinandy P, Braun T, Mendler L.: Myostatin and IGF-I signaling in end-stage human heart failure: a qRT-PCR study., J Transl Med. 2015 Jan 16;13:1. doi: 10.1186/s12967-014-0365-0., 2015 | Pickard JM, Bøtker HE, Crimi G, Davidson B, Davidson SM, Dutka D, Ferdinandy P, Ganske R, Garcia-Dorado D, Giricz Z, Gourine AV, Heusch G, Kharbanda R, Kleinbongard P, MacAllister R, McIntyre C, Meybohm P, Prunier F, Redington A, Robertson NJ, Suleiman MS, Vanezis A, Walsh S, Yellon DM, Hausenloy DJ.: Remote ischemic conditioning: from experimental observation to clinical application: report from the 8th Biennial Hatter Cardiovascular Institute Workshop., Basic Res Cardiol. 2015 Jan;110(1):453., 2015 | Varga ZV, Zvara A, Faragó N, Kocsis GF, Pipicz M, Gáspár R, Bencsik P, Görbe A, Csonka C, Puskás LG, Thum T, Csont T, Ferdinandy P.: MicroRNAs associated with ischemia-reperfusion injury and cardioprotection by ischemic pre- and postconditioning: protectomiRs., Am J Physiol Heart Circ Physiol. 2014 Jul 15;307(2):H216-27., 2014 | Pavo N, Emmert MY, Giricz Z, Varga ZV, Ankersmit HJ, Maurer G, Hoerstrup SP, Ferdinandy P, Wu JC, Gyöngyösi M.: On-line visualization of ischemic burden during repetitive ischemia/reperfusion., JACC Cardiovasc Imaging. 2014 Sep;7(9):956-8., 2014 | Schulz R, Görge PM, Görbe A, Ferdinandy P, Lampe PD, Leybaert L.: Connexin 43 is an emerging therapeutic target in ischemia/reperfusion injury, cardioprotection and neuroprotection, Pharmacol Ther. 2015 Sep;153:90-106., 2015 | Madonna R, Cadeddu C, Deidda M, Giricz Z, Madeddu C, Mele D, Monte I, Novo G, Pagliaro P, Pepe A, Spallarossa P, Tocchetti CG, Varga ZV, Zito C, Geng YJ, Mercuro G, Ferdinandy P.: Cardioprotection by gene therapy: A review paper on behalf of the Working Group on Drug Cardiotoxicity and Cardioprotection of the Italian Society of Cardiology., Int J Cardiol. 2015 Jul 15;191:203-10., 2015 | Csonka C, Kupai K, Bencsik P, Görbe A, Pálóczi J, Zvara A, Puskás LG, Csont T, Ferdinandy P.: Cholesterol-enriched diet inhibits cardioprotection by ATP-sensitive K+ channel activators cromakalim and diazoxide, Am J Physiol Heart Circ Physiol. 306(3):H405-13., 2014 | T. Baranyai, Z. Giricz, M. Sárközy, H. Vágó, C. Czimbalmos, L. Tóth, B. Merkely, M. Gyöngyösi, P. Ferdinandy: Ischemic postconditioning prevents ischemia-induced acute myocardial dilation and limits cardiac edema in a clinically relevant, closed-chest pig model of acute myocardia, CARDIOLOGIA HUNGARICA 45:(Suppl. D) p. D21. (2015), 2015 | Macejovska D, Pavo N, Zlabinger K, Ferdinandy P, Mauer G, Gyöngyösi M: Difference in cardioprotective effects of ischemic post-conditioning and remote conditioning in porcine closed-chest reperfused myocardium, Annual meeting of the Austrian Society of Cardiology, Salzburg, Wien Klin Wochenschr. 2015; 127:S42-S3, 2015 | Lukovic D, Pavo N, Zlabinger K, Gugerell A, Winkler J, Giricz Z, Baranyai T, Ferdinandy P, Mauer G, Gyöngyösi M: Ischemic postconditioning modulates focal adhesion signaling pathway in porcine model, Annual meeting of the Austrian Society of Cardiology, Salzburg, Wien Klin Wochenschr. 2016;128:S231-S2, 2016 | Giricz Z: AZ ISZKÉMIÁS PRE-, POSZT- ÉS TÁVOLI KONDÍCIONÁLÁS ÖSSZEHASONLÍTÁSA EGY KLINIKAILAG RELEVÁNS, SERTÉS, AKUT MIOKARDIÁLIS INFARKTUS MODELLBEN, Magyar Farmakológiai, Anatómus, Mikrocirkulációs és Élettani Társaságok Közös Tudományos Konferenciája, Pécs, 2016 |

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